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Throat anatomy
Throat anatomy


Oropharynx
Oropharynx


Throat or larynx cancer

Definition:

Throat cancer is cancer of the vocal cords, voice box (larynx), or other areas of the throat.



Alternative Names:

Vocal cord cancer; Throat cancer; Laryngeal cancer; Cancer of the glottis; Cancer of oropharynx or hypopharynx



Causes:

People who smoke or use tobacco are at risk of developing throat cancer. Drinking too much alcohol over a long time also increases risk. Smoking and drinking alcohol combined lead to an increased risk of throat cancer.

Most throat cancers develop in adults older than 50. Men are 10 times more likely than women to develop throat cancers.



Symptoms:

Symptoms of throat cancer include any of the following:

  • Abnormal (high-pitched) breathing sounds
  • Cough
  • Coughing up blood
  • Difficulty swallowing
  • Hoarseness that does not get better in 1 to 2 weeks
  • Neck or ear pain
  • Sore throat that does not get better in 1 to 2 weeks, even with antibiotics
  • Swelling or lumps in the neck
  • Weight loss not due to dieting


Exams and Tests:

The doctor will perform a physical exam. This may show a lump on the outside of the neck.

The doctor may look in your throat or nose using a flexible tube with a small camera at the end.

Other tests that may ordered include:



Treatment:

The goal of treatment is to completely remove the cancer and prevent it from spreading to other parts of the body.

When the tumor is small, either surgery or radiation therapy alone can be used to remove the tumor.

When the tumor is larger or has spread to lymph nodes in the neck, a combination of radiation and chemotherapy is often used to save the voice box (vocal cords). If this is not possible, the voice box is removed. This surgery is called laryngectomy .



Support Groups:

You can ease the stress of illness by joining a cancer support group . Sharing with others who have common experiences and problems can help you not feel alone.



Outlook (Prognosis):

Throat cancers may be cured when detected early. If the cancer has spread to surrounding tissues or lymph nodes in the neck, about half of patients can be cured. If the cancer has spread (metastasized) to parts of the body outside the head and neck, the cancer is not curable. Treatment is aimed at prolonging and improving quality of life.

After treatment, therapy is needed to help with speech and swallowing. If the person is not able to swallow, a feeding tube will be needed.



Possible Complications:

When to Contact a Medical Professional:

Call your health care provider if:

  • You have symptoms of throat cancer, especially hoarseness or a change in voice with no obvious cause that lasts longer than 3 weeks
  • You find a lump in your neck that does not go away in 3 weeks


Prevention:

Do not smoke or use other tobacco. Limit or avoid alcohol use.



References:

Armstrong WB, Vokes DE, Maisel RH. Malignant tumors of thelarynx. In: Flint PW, Haughey BH, Lund VJ, et al., eds. Cummings Otolaryngology Head and Neck Surgery. 5th ed. Philadelphia, Pa: Elsevier Mosby; 2010:chap 107.

National Cancer Institute: PDQ Laryngeal Cancer Treatment. Bethesda, Md: National Cancer Institute. Date last modified: February 15, 2013. Available at: http://cancer.gov/cancertopics/pdq/treatment/laryngeal/HealthProfessional. Accessed: February 3, 2014.

National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines): Head and neck cancers. Version 2.2013. Available at: http://www.nccn.org/professionals/physician_gls/pdf/head-and-neck.pdf. Accessed: February 3, 2014.




Review Date: 2/3/2014
Reviewed By: Ashutosh Kacker, MD, FACS, Professor of Clinical Otolaryngology, Weill Cornell Medical College, and Attending Otolaryngologist, New York-Presbyterian Hospital, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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Atlantic Medical Group
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Morristown Medical Center

100 Madison Avenue
Morristown, NJ 07960
973-971-5000

Overlook Medical Center

99 Beauvoir Avenue
Summit, NJ 07901
908-522-2000

Newton Medical Center

175 High Street
Newton, NJ 07860
973-383-2121

Chilton Medical Center

97 West Parkway
Pompton Plains, NJ 07444
973-831-5000

Goryeb Children's Hospital

100 Madison Avenue
Morristown, NJ 07960
973-971-5000

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Atlantic Medical Group

More than 600 community-based health care providers.
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