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Thrombus
Thrombus


Janeway lesion on the finger
Janeway lesion on the finger


Deep venous thrombosis, ileofemoral
Deep venous thrombosis, ileofemoral


Blood clots

Definition:

Blood clots are clumps that occur when blood hardens from a liquid to a solid.

  • A blood clot that forms inside one of your veins or arteries is called a thrombus. A thrombus may also form in your heart.
  • A thrombus that breaks loose and travels from one┬álocation in the body to another is called an embolus .

A thrombus or embolus can partly or completely block the flow of blood in a blood vessel.

  • A blockage in an artery may prevent oxygen from reaching the tissues in that area. This is called ischemia. If ischemia is not treated promptly, it can lead to tissue damage or death.
  • A blockage in the vein will usually cause fluid buildup and swelling.


Alternative Names:

Clot; Emboli; Thrombi; Hypercoagulable state



Causes:

Situations in which a blood clot is more likely to form include:

  • Being on long-term bed rest
  • Crossing your legs for long periods when sitting, or sitting for long periods, such as in a plane or car
  • During and after pregnancy
  • Not having enough water in your body (dehydration)
  • Taking birth control pills or estrogen hormones (especially in women who smoke)
  • Long-term use of an intravenous catheter

Blood clots are also more likely in people with cancer, recent surgery or injury, obesity, and liver or kidney disease.

A buildup of cholesterol that narrows an artery may change or slow the flow of blood, making it easier for a blood clot or thrombus to form.

Conditions that are passed down through families (inherited) may make you more likely to form abnormal blood clots. Inherited conditions that affect clotting are:

A blood clot may block an artery or vein in the heart, affecting the:



References:

Schafer AI. Thrombotic disorders: hypercoagulable states. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 179.




Review Date: 5/29/2014
Reviewed By: Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

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Morristown Medical Center

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Overlook Medical Center

99 Beauvoir Avenue
Summit, NJ 07901
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Newton Medical Center

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Newton, NJ 07860
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Pompton Plains, NJ 07444
973-831-5000

Goryeb Children's Hospital

100 Madison Avenue
Morristown, NJ 07960
973-971-5000

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